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Brief Introduction Of Spinosad






     Spinosad is a macrolide pollution-free and highly effective biological pesticide that the Saccharopolyspora spinosa extract from fermentation broth. The parental strains actinomycetes Saccharopolyspora which produce spinosad was originally isolated from an abandoned winery in Caribbean. The researchers found that this bacteria can produce high insecticidal activity compounds, practical products are spinosyn A and spinosyn D mixture, so it called spinosad. Spinosadís mode of action can be sustained activating target insect nicotinic acetylcholine receptors, but its binding site is different from nicotine and imidacloprid. Spinosad can also affect GABA receptors, but the mechanism of action is unclear. It is not known whether have cross- resistance with other types insecticides. These compounds can cause target phytophagous insects such as caterpillars, leafminers, thrips, leaf eating beetles rapid death, despite the management strong demand used for the resistance does not appear, the moderate residual activity of the spinosad product is reduced the likelihood of resistance and groups occurrence. When applying in 12-150g/hm, there is not found injury.

Solubility: can be in any proportion mixed with alcohols, aliphatic hydrocarbons, aromatic hydrocarbons, halogenated hydrocarbons, esters, ethers and ketones miscible.

Stability: it is relatively stable with metals and metal ions within 28days. Through a variety of ways to degrade in the environment, mainly light degradation and microbial degradation, eventually change into carbon, hydrogen, oxygen, nitrogen and other natural ingredients. See light decomposition, hydrolysis was relatively fast, the half-life in water is 1 day; the half-life in soil is 9-10 days.

Characterized as: its mechanism of action is considered to be the role of nicotinic acetylcholine receptor body that can continue active target insects nicotinic acetylcholine receptors, but its binding site is different from nicotine and imidacloprid. Spinosad can also affect GABA receptors, but the mechanism is unclear. Can make pests quickly palsy, paralysis, and finally death. Its insecticidal speeds can be comparable with chemical pesticides. Safety, and no cross-resistance with current insecticides, used as a low toxicity, high efficiency, low residue biocides, both highly effective insecticidal properties, and have the security features to beneficial insects and mammals, more suitable for pollution-free vegetables, fruit production applications. Is a low toxicity, high efficiency, broad-spectrum insecticide.

Toxicity: female rats acute oral LD50> 5000 mg/kg, the male is 3738 mg/kg, mice >5000 mg/kg, rabbit acute dermal LD50> 5000 mg/kg. Not stimulation to the skin, slight irritation to the eyes, two days to disappear. Spinosad degradable in the environment, without enrichment, do not pollute the environment.

Mechanism: to pests have fast contact and stomach poison effect, have a strong infiltration on the leaves, can kill pests under the skin, vinca longer, for some pests have ovicidal action. Not suction effect. Can effectively control Lepidoptera, Diptera and Thysanoptera pests, also can good prevent some pest species on Coleoptera and Lepidoptera which feeding a large number of leaves, the prevention to sucking pests and mites is less effective. To insect predators is relative safer, because insecticidal mechanism of action was unique, has not yet found the reported that have cross resistance with other insecticides. Safety and without injury to plants, suitable for vegetables, fruit, horticulture, crop. Insecticidal effect was less affected by the rains.






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pharmaceutical raw materialsspinosad manufacturer Source:www.cospcn.com


Posted on 2013-06-17, By: *

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