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Fordyce Fordyce spots are normal large, superficial sebaceous (oil-producing) glands seen on the moist tissue that lines some organs and body cavities (mucosal surfaces). The "spots" are asymptomatic and can be found on the head of the penis, the inner foreskin, and, most commonly, at the border of the lips. These sebaceous glands are not associated with hair follicles. These lesions are asymptomatic, but itching or irritation may occur if people treat the bumps inappropriately. Cystic Acne Cystic acne is one of the most severe kinds of acne. The cysts formed on the skin as a result of this are much larger than ordinary pimples and are also very painful. These cysts are generally filled with pus.